GATOR1-related epilepsies caused by DEPDC5, NPRL2, and NPRL3 variations exhibit various phenotypes consisting of sleep-related focal hypermotor seizures, infantile spasms, and other focal epilepsies, including frontal, temporal, occipital, parietal, centrotemporal epilepsies [10]. The gene discussed is NPRL2; the disease is infantile spasms.