We found no evidence for significant differences in the glycosylation patterns of circulating IgG3 between our patient with diabetic nephropathy, a healthy control and a patient with THSD7A-associated MN, since serum IgG3 gave a Western blot signal at the same height in all cases, indicating similar molecular weight (Supplemental Figures 3b, 4b). The gene discussed is IGHG3; the disease is diabetic kidney disease.