Among the GC-associated cancer genes identified in the TCGA reports6, the focal gene amplification of CCND1 (23% for Rs, 0% for NRs), MET (38% for Rs, 18% for NRs), and MDM2 (23% for Rs, 0% for NRs) was observed in the R group (Fig. 2d). Here, CCND1 is linked to cancer.