TGFB1 and cancer: In addition, gene sets associated with cell-to-cell and cell-to-ECM interactions, such as “Transforming growth factor-β (TGF-β) signaling,” “Angiogenesis,” and “Wnt/β-Catenin signaling,” were enriched in the NR group (Fig. 4a and Supplementary Fig. 11a), consistent with the GSEA results from human cancer cells.