Inflammatory markers, hypersensitive C-reactive protein (hs-CRP), and homocysteine (HCY) (HCY-induced oxidative stress and inflammation via Nox4/NF-κB pathway) [21] have been reported to be associated with SCH [22, 23], we additionally explored the relationship of gut microbiota, inflammatory markers, and treatment response. The gene discussed is CRP; the disease is spindle cell hemangioma.