SRSF1 and cancer: In agreement with the proliferative and oncogenic functions of SRSF1 [29, 30], the depletion of SRSF1 in healthy neurons leads to down-regulation of markers of the G1/S cell cycle transition and mitosis (Supplementary Figure 1A) as well as of cell proliferation and cancer markers [49, 50] (Supplementary Figure 1B).