C9orf72 and amyotrophic lateral sclerosis: The nuclear export of 177 annotated transcripts, which include 137 mRNAs, is altered in C9ORF72-ALS neurons treated with SRSF1-RNAi representing 0.4% of the transcriptome while 202 mRNAs have altered nuclear export in healthy neurons depleted of SRSF1 (Table S9).