Based on a prospective cohort study of 239 women with breast cancer of childbearing age (follow up for 6 months), high AMH, compared to normal and low-basic AMH, led to a lower prevalence of chemotherapy-related amenorrhea (CRA), indicating that a high level of AMH residue after chemotherapy has certain protective effect on ovarian function, but it still needs further discussion [21]. The gene discussed is AMH; the disease is amenorrhea.