Low nuclear LIG4 was significantly associated with larger residual tumours (p = 0.006), poor response to platinum-based chemotherapy (p = 0.049) (Table S4), poor PFS (p = 0.041) (Figure 1Q) and poor OS (p = 0.016) (Figure 1R) compared with high nuclear LIG4 expressing tumours. The gene discussed is LIG4; the disease is neoplasm.