Consistent with the findings derived from tumor tissues, primary p18mt;Brca1+/- and p18mt;Gata3+/- tumor cells also exhibited a typical mesenchymal-like morphology with a high level of EMT markers, whereas, epithelial-like morphology were observed in p18mt and MMTV-PYMT tumor cells (Figure 5C, E). This evidence concerns the gene BRCA1 and neoplasm.