We found that nAPCs generated from mature bone marrow-derived neutrophils treated with SLE-IC, Ova-IC + GM-CSF, or GM-CSF (i.e., anti-Ova alone) were equivalent to neutrophils in their ability to phagocytose E. coli and IgG coated beads (Fig. 3a) and generate ROS in response to E. coli and Zymosan (Fig. 3b). The gene discussed is CSF2; the disease is systemic lupus erythematosus.