Prior publications have additionally highlighted the impact of MIR22HG on the proliferation and apoptosis of a variety of human malignancies, along with reports suggesting that MIR22HG can either act as a tumor suppressor or promoter in lung cancer, glioblastoma and hepatocellular carcinoma (HCC), for instance [10, 11, 31, 41]. The gene discussed is MIR22HG; the disease is lung cancer.