According to the analysis of different tumor types, SNHG12 high expression has a significant correlation with poor OS in the patients with digestive system cancer (HR = 2.12, 95% = 1.43–3.15, P = 0.0002), nervous system (HR = 2.41, 95% = 1.17–4.97, P = 0.02), respiratory system carcinomas (HR = 1.94, 95% = 1.15–3.28, P = 0.01), cancers of the reproductive system (HR = 2.40, 95% = 1.12–5.15, P = 0.03), and locomotor system (HR = 2.41, 95% = 1.17–4.97, P = 0.02). The gene discussed is SNHG12; the disease is reproductive system cancer.