MYC and acute myeloid leukemia: Aberrant transcription factors encoded by AML-related rearrangements such as AML1-ETO (RUNX1-CBFA2T1), PML-RARα, and ZBTB16 (PLZF)-RARα have been reported to induce Wnt signaling, leading eventually to the upregulation of MYC [638–640].