MTT and Celigo experiments were used to test the proliferative ability of the cells and found that, following VIM overexpression, the suppression of cell proliferation caused by WDR43 knockdown was significantly recovered, while tumor cells overexpressing VIM alone showed stronger proliferative ability (Fig. 8b, c; Additional file 9: Table S5 and Additional file 10: Table S6). This evidence concerns the gene WDR43 and neoplasm.