Based on the results of the dual luciferase reporter gene assay, Ago2-RIP assay, RNA pull-down and RT-qPCR, SBF2-AS1 can serve as a sponge that competitively binds to miR-122-5p, miR-362-3p, miR-188-5p, miR-30a, miR-142-3p, miR-361-5p, miR-151-3p and so on (Table 2), thus regulating biological processes in tumor cells. The gene discussed is SBF2; the disease is neoplasm.