BIRC5 and neoplasm: To further evaluate BIRC5 as a potential target for tumor therapy, we analyzed the expression patterns of BIRC5, and found that BIRC5 was up-regulated more than 19-fold in tumor tissues relative to non-tumor samples (Fig. 2A), and BIRC5 protein expression levels were much higher in the tumor samples than those in non-tumor samples (Fig. 2B).