In particular, the following mechanisms are activated: (1) nargirin activates glutathione (GSH), ensuring a new antioxidant defense mechanism; (2) naringin prevents the progression of hyperglycemia by increasing hepatic glycolysis and lowering hepatic gluconeogenesis; (3) nargirin shows antidiabetic effects; (4) naringin inhibits the hyperglycemia-induced NF-κB pathway [156]. The gene discussed is NFKB1; the disease is Hyperglycemia.