At the time of HD initiation, a patient presenting with malnutrition has a high mortality risk on the basis of low nutrition markers, such as geriatric nutritional risk index (GNRI) [20], subjective global assessment [21], low body mass index (BMI) [22], low serum levels of albumin [20] and cholesterol [21], and low food intake [23]. This evidence concerns the gene ALB and nutritional deficiency disease.