The extracts led to an increase in antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), and a reduction in glutathione (GSH), oxidative stress biomarker including thiobarbituric reactive species (TBARS), and lipid hydroperoxides (LOOH) in the liver tissues of T2DM group over 4 weeks of treatment period compared to the STZ-induced diabetic group. Here, SOD1 is linked to type 2 diabetes mellitus.