Despite many hallmarks found for each of these diseases, such as the presence of amyloid-β extracellular plaques and intracellular hyper-phosphorylated Tau neurofibrillary tangles in Alzheimer’s disease or α-synuclein in Parkinson’s disease, there is no known way to prevent or cure many of them [6]. The gene discussed is MAPT; the disease is Parkinson disease.