MAPT and Alzheimer disease: DNAJA2, a member of this JDP family, was recently identified as a potent suppressor of tau aggregation, capable of effectively preventing the seeding of tau and formation of amyloids in cells (Mok et al., 2018; Abisambra et al., 2012), with DNAJA2 levels being selectively increased in AD patient neuronal cells (Mok et al., 2018).