Low-CYP3A4 expression and high-CDC20 expression could be seen in HCC cases (Figure 8(a,d)), and both of the two hub genes were correlated with ACE2 expression (Figure 8(b,e)) and prognoses of HCC patients (p < 0.05, Figure 8(c,f)). The gene discussed is CDC20; the disease is hepatocellular carcinoma.