A previous report has shown that ectopic expression of IL‐36γ in tumor cells promotes Th1 cell polarization, CD8+ T cell activation and anti‐tumor immunity.[44] However, results from our scRNA‐seq analysis suggested that Il1f9 was barely expressed in epithelial tumor cells in KL mouse model, which is consistent with recent studies.[51, 52] In addition, Il1rl2 was expressed in neutrophils, endothelial cells, and epithelial tumor cells but not in T cells. Here, IL1RL2 is linked to neoplasm.