It has been shown that the expression of IL‐36γ is upregulated in inflamed skin and in colon tissues.[32, 33, 34, 35, 36, 37] Here, we found that IL‐36γ was upregulated in NSCLC tumor tissues compared to the normal lung tissues and the levels of Il1f9 were higher in advanced tumors than in early‐stage tumors from the KL mice. The gene discussed is IL36G; the disease is non-small cell lung carcinoma.