MKI67 and neoplasm: Compared to AZD4547 and BI6727 alone that had only minor anti‐tumor effects, the drug combination showed significantly (P < 0.05) greater inhibition of tumor growth (Fig 2F–H), paralleled by significantly suppressed proliferation (Ki‐67) and increased apoptosis (caspase‐3), despite similar changes in mice body weights compared to single agents after 3‐week treatment (Appendix Fig S2K–M).