FANCE and Friedreich ataxia: Reproductive defects are the most consistent phenotypes seen in FA mouse models [Fanca−/−, Fancb−/−  Fancc−/−, Fancd1, Fancd2−/−, Fance−/−, Fancg−/−, Fancj−/−, Fancl−/−, Fancm−/− and Fancp−/− (18–22)].