Among the DE miRNAs, compared to HC exosomes and DM-nonILD-MSA16(-) exosomes, 38 and 51 miRNAs were significantly upregulated, while 21 and 33 miRNAs were significantly downregulated in DM-ILD-MDA5 Ab(+) exosomes, respectively. Here, IFIH1 is linked to dermatomyositis.