The use of toceranib, as a conditioner in association with immune therapy in cancer patients, would also promote an antagonistic action toward VEGF, as well as add to the collective action to tilt the inflammatory environment in the tumor toward a less angiogenic environment with fewer immunosuppressive lymphocytes and more Th1 cells and M1 macrophages (1, 3, 38, 52–56). Here, VEGFA is linked to neoplasm.