MSRB3 and deafness: The area of CFA10:8–8.6 Mb has been found to be associated with at least two morphological (ear type and body size) (3, 5, 24) and two behavioral (boldness and fear) traits (4, 7), including genes such as MSRB3 and HMGA2. MSRB3 has been reported to be associated with human deafness (42, 49), brain morphology, and late-onset Alzheimer's disease (50).