The driver genes ERBB2, HDAC1, PARP1, ERBB3, FGFR3, mTOR, AXL, EZH2, FGFR1, FGFR2, CSF1R, KIT, FGFR4, RET, and ERBB4 are key targets in the treatment of BLCA. Here, FGFR4 is linked to bladder transitional cell carcinoma.