Multivariate analysis demonstrated that lymph node metastasis, TIM-3+ TILs infiltration, and CEACAM1 expression were independent prognostic factors for OS, while lymph node metastasis and CEACAM1 expression could be regarded as independent prognostic factors of DFS (all p < 0.05, Tables 3 and 4). The gene discussed is HAVCR2; the disease is metastatic malignant neoplasm in the lymph nodes.