Also in support of a protective role of IFNα/β, another group found inborn errors of IFNα/β immunity and an increased prevalence of autoantibodies against IFNα/β, including IFNα and IFNω, in critically ill COVID-19 patients, compared to those with mild disease or asymptomatic infection (25, 26). The gene discussed is IFNA2; the disease is COVID-19.