Furthermore, combined analysis of MeRIP-seq and RNA-Seq data demonstrated that unique m6A-modified transcripts were highly relevant to cardiac fibrosis, myocardial hypertrophy, and myocardial energy metabolism; therefore, we focused on genes critical for these processes, including Mef2a, Klf15, Bcl2l2, Cd36, and Slc25a33 (Figure 4C and Table 2). Here, KLF15 is linked to cardiac hypertrophy.