Altered methylation in H19 has been broadly documented to be associated with infertile males affected by oligozoospermia, asthenozoospermia, teratozoospermia, OA, AT, and OAT (Marques et al., 2004, 2008, 2010; Kobayashi et al., 2007; Boissonnas et al., 2010; Minor et al., 2011; Rotondo et al., 2013; Li et al., 2016; Dong et al., 2017; Bruno et al., 2018; Peng et al., 2018). The gene discussed is H19; the disease is Infertility.