TGFB1 and Myocardial fibrosis: Eosinophils are a subset of circulating innate immune cells that contribute to cardiac cell death and myocardial fibrosis through their abundant mediators, such as TGF-β, EOS cationic protein (ECP), EOS-derived neurotoxin (EDN), major basic protein (MBP), EOS peroxidase (EPO), lysosomal hydrolytic enzymes, EOS peroxidase, and type 2 cytokines (Jacobsen et al., 2012; Rosenberg et al., 2013; Liu et al., 2020; Toor et al., 2020).