NPPB and cardiac hypertrophy: In chemokine Fraktalkine receptor CX3CR1-deficient Cx3cr1GFP/GFP mice, TAC-induced reductions in EF and cardiac output were fully recovered, along with reduced HW/BW, cardiac damage marker aldolase, cardiac hypertrophy and its marker B-type naturetic peptide (BNP), and cardiac fibrosis (Weisheit et al., 2021).