Activated PI3K/AKT can catalyze the phosphorylation of a series of proteins, ultimately promoting the growth and proliferation of tumor cells, inhibiting apoptosis, promoting invasion and metastasis, regulating the growth and angiogenesis of endothelial cells, and increasing the sensitivity to radiation (Lee et al., 2015; Alzahrani, 2019). This evidence concerns the gene AKT1 and neoplasm.