Importantly, AGK has been identified as a key oncogene that is highly expressed in a range of tumor types, such as prostate cancer (Spiegel and Milstien, 2005; Nouh et al., 2009; Zeng et al., 2009), breast cancer (Wang et al., 2014), cervical squamous cell carcinoma (Sun et al., 2016), and esophageal squamous cell carcinoma (ESCC) (Chen et al., 2013). This evidence concerns the gene AGK and prostate carcinoma.