Genomic alterations of PAC occurred in TP53 (n = 39, 52.70%), KRAS (n = 38, 51.35%), MUC17 (n = 26, 35.14%), GNAS (n = 23, 31.08%), and CABIN1 (n = 19, 25.68%), in decreasing order (Supplementary Figure 1A). The gene discussed is TP53; the disease is gonorrhea.