PTK7 and invasive breast carcinoma: To explore the potential role of PTK7 in breast cancer, we analyzed PTK7 expression in breast cancer using an RNA-Seq datasets GEPIA: Gene Expression Profiling Interactive Analysis system (http://gepia.cancer-pku.cn/) and found that PTK7 transcription levels are significantly higher in breast invasive carcinoma (BRCA) tissues (n = 1,085) than that in matched non-tumor tissues (n = 291), suggesting a potential role of PTK7 in breast cancer (Figure 1A).