Moreover, the efficacy of other PD-1 or PD-L1 inhibitors, like pembrolizumab (PEARIS, NCT02504372), durvalumab (BR31, NCT02273375), and atezolizumab (IMPOWER010, NCT02486718), in treating early stage lung cancer is being evaluated in ongoing clinical trials. This evidence concerns the gene PDCD1 and lung cancer.