Transducing of Human CRC cells (HCT116 cells) with small hairpin RNA (shRNA) targeting NUFIP1, FAM92A1, NEBL, PLEKHS1, PRPF4, CGREF1, POLR1B, HILPDA, TAF1D, or NUDCD1 attenuated growth. This evidence concerns the gene PRPF4 and colorectal carcinoma.