RFC4 and hepatocellular carcinoma: We identified both miR-4666a-5p and miR-6124 as potential upstream regulators of ALYREF and eIF4A3 and identified the overexpression of eight hub genes (BIRC5, MCM2, MCM3, MCM6, NOP56, PCNA, RFC4 and SNRPD1) in HCC tissues.