CXCL8 and type 1 diabetes mellitus: Figure 9 shows that the immunological target proteins including IL10, CXCL8, and TNF are located in the PPI networks with a top degree of interaction, indicating that this PPI network is associated with immunological activities. It was stated that humans' chemokines have been associated with, or implicated in, the pathogenesis of type 1 diabetes [55].