Similarly, luteolin attenuated sepsis-induced ALI in mice by suppressing ICAM-1, NF-κB, oxidative stress, and the iNOS pathway [123], and protected against mercuric chloride-induced lung injury in mice by preventing NF-κB activation and activating Akt/Nrf2 [124]. The gene discussed is NFKB1; the disease is Sepsis.