AGTR1 and COVID-19: Nrf2-interacting nutrients (berberine, curcumin, epigallocatechin gallate, genistein, quercetin, resveratrol, sulforaphane) reduce insulin resistance, endothelial damage, lung injury, and cytokine storm and act on several mechanisms such as mTOR, PPARγ, NF-κB, ERK, etc. Nrf2-interacting nutrients can promote the mitigation of COVID-19 severity through the endoplasmic reticulum stress, ACE-angiotensin-II-AT1R axis (AT1R).