Among 97 gastric cancers, EBV positivity was observed in 6 cases (6.2%), MSI in 13 cases (13.4%), E-cadherin aberrant expression in 28 cases (28.9%), p53 aberrant expression in 31 cases (31.9%), and p53 normal expression in 19 cases (19.6%). The gene discussed is CDH1; the disease is gastric cancer.