AP1S3-related KEGG pathways enriched comprised protein processing in the endoplasmic reticulum, lysosome, apoptosis, proteoglycans in cancer, other glycan degradation, shigellosis, arrhythmogenic right ventricular cardiomyopathy, Salmonella infection, glycosaminoglycan biosynthesis-heparan sulfate/heparin, and sphingolipid metabolism (Figure 3(d)). This evidence concerns the gene AP1S3 and arrhythmogenic right ventricular cardiomyopathy.