AP1S3 and central nervous system cancer: Figure 6(a) reveals that AP1S3 was silenced in SW1783 and U373 after transfection of si-AP1S3. Next, CCK-8 and Transwell assays were conducted to determine the impacts of ablated AP1S3 on cell proliferation, invasion, and migration. After the glioma cells were transfected with si-AP1S3, the cell proliferation ability was reduced (Figure 6(b)). Besides, Transwell assays showed that silencing AP1S3 suppressed cell migration and invasion ability (Figures 6(c) and 6(d)).