Recent publications also reported therapeutic success of checkpoint inhibition in Hodgkin lymphoma (63), and pembrolizumab and anti PD-L1 (atezolizumab) are currently setting the way to improve the outcome in triple-negative breast carcinoma, as PD-L1 positive patients reached 25-month survival compared to 18 months in the control group (64). Here, CD274 is linked to triple-negative breast carcinoma.