More recently, B-cell maturation antigen (BCMA) CAR T-cells (idecabtagene vicleucel) were approved for therapy of advanced myeloma (72, 73), brexucabtagene autoleucel for mantle cell lymphoma, and lisocabtagene maraleucel for relapsed or refractory large B-cell lymphoma (Figure 1). The gene discussed is TNFRSF17; the disease is mantle cell lymphoma.