Compared with HCs, the levels of blood total protein, globulin, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total bilirubin, direct bilirubin, indirect bilirubin, γ-glutamyl transpeptidase (GGT) and eosinophils were increased in PBC patients (Table 1). Here, CCL27 is linked to primary biliary cholangitis.