Th17 induce neuronal cell death and promote neuronal toxicity in experimental autoimmune encephalomyelitis, the animal model of multiple sclerosis (35) and IL-17 mRNA is overexpressed in active MS brain lesions (36), while IL-17 production from central nervous system resident T lymphocytes and glial cells are associated with disease-activity (37). Here, IL17A is linked to myeloid sarcoma.