ARHGAP6 and Autoimmunity: To further explore the effect of BLM on the expression of candidate Yaa locus genes (TLR7, TLR8, Arhgap6, Msl3, and Tceanc) associated with autoimmunity, quantitative real-time PCR (RT-qPCR) was performed to compare the mRNA expression of these genes in the lung tissues of both BLM and PBS groups in Yaa and BXSB mice.