Apart from ependymomas, radiomics has also shown potential in creating phenotypic signatures of glioma genotypes such as isocitrate dehydrogenase (IDH) (24–26), epidermal growth factor receptor (EGFR) (27), and O6-methylguanine-DNA-methyl-transferase (MGMT) (28–31). This evidence concerns the gene EGFR and central nervous system cancer.