APOE and atherosclerosis: Due to high dysferlin expression in atherosclerotic and aortic tissues (Figures 1A,B) and its role in endothelial adhesion during angiogenic stimulation (Sharma et al., 2010), normolipidemic and dyslipidemic ApoE-null mice – representing very slow and accelerated models of atherosclerosis, respectively, were bred to WT and dysferlin KO animals.