L. casei and L. acidophilus ↓ arthritis score; ↑ IL-4; ↑ IL-10; ↓ IL-6; ↓ TNF; ↓ IL-1β; ↓ IL-17; ↓ CAT; ↓ lipid peroxidation; ↑ GSH; ↑ GPx; ↑ SOD. The gene discussed is IL4; the disease is arthritic joint disease.